In the training cohort, the study found that early mortality patients in the training cohort were more likely to be men (p = 0.019), single (p = 0.004), with advanced T (p = 0.025) and N (p = 0.001) stage, unknown fibrosis score (p = 0.040), positive AFP level (p = 0.032), larger tumor size (p = 0.001), lung metastases (p < 0.001), less cancer-directed surgery (p < 0.001), less radiation (p < 0.001), and less chemotherapy (p < 0.001), whereas other clinical characteristics were insignificant (Table 3). This evidence concerns the gene AFP and cancer.