HOTAIR and cervical cancer: In addition, after HOTAIR was silenced, the expression of miR206 was up-regulated, while the expression of miR206 downstream target protein megakaryoblastic leukemia 1 (MKL1) was down-regulated, and it could increase the distribution of MKL1 in the cytoplasm, indicating that HOTAIR promotes the expression of MKL1 by inhibiting the expression of miR206 And change the distribution of MKL1 cells to promote cervical cancer invasion and migration.