While the proportions of infiltrated tumor-killing immune cells, such as T cells CD8, T cells CD4 memory activated, T cells regulatory (Tregs), T cells gamma delta, NK cells activated, and plasma cells in the lower-risk category were much higher, which play crucial roles in the progression of BRCA and function as the tumor suppressors21–23 (Fig. 8C, D). Here, CD8A is linked to neoplasm.