Gabra1-IRES-cre; Ptger3flox mice displayed a marked attenuation of influenza-induced sickness behaviour similar to ibuprofen treatment, whereas no effect was observed in either Pdyn-IRES-cre; Ptger3flox or Oxtr-IRES-cre; Ptger3flox mice (Fig. 3b and Extended Data Fig. 8a). The gene discussed is GABRA1; the disease is influenza.