KTN1 has been reported to play important roles in many neuropsychiatric or neurodegenerative diseases/phenotypes, including attention-deficit/hyperactivity disorder (ADHD)58,59, Parkinson’s disease (PD)60–63, heroin dependence64, marijuana dependence65, alcohol dependence66, and cognitive dysfunction in the elderly67. This evidence concerns the gene KTN1 and Parkinson disease.