In addition to ontologies related to cell contacts and signaling axes with known relevance in AML (G-protein coupled receptors, phosphatidylinositol-mediated signaling, JAK-STAT), GO-BPs characterizing miR-126high fractions prominently contained lymphoid categories, and we confirmed strong and consistent upregulation of bona fide lymphoid genes, including RAG1, RAG2, CD79A, CD79B, ZAP70, IGH genes and CD7 in the individual miR-126high samples across all 4 patients, irrespective of chemotherapy (Supplementary Fig. 4D). Here, ZAP70 is linked to acute myeloid leukemia.