These cytokines in turn influence Immunoglobulin E (IgE) levels and eosinophilia (Isnard and Chevillard, 2008; He et al., 2008) which have been associated with infection/re-infection or resistance to schistosome infections (Demeure et al., 1993; Caldas et al., 2000; Gatlin et al., 2009; Figueiredo et al., 2012; Ndombi et al., 2018). Here, IGHE is linked to infection.