A fifth to a third of hospitalizedpatients have evidence of myocardial injury, defined as high cardiac troponin (cTn)levels at admission.(4,5,9-14) In severe cases,SARS-CoV-2 progresses from ACE2-dependent alveolar damage and hypoxia to systemicinflammatory response syndrome, acute respiratory distress syndrome (ARDS), and anexaggerated release of cytokines. The gene discussed is ACE2; the disease is acute respiratory distress syndrome.