10 Perez Perez AL AL Grodin Grodin JL JL Wu Wu Y Y Hernandez Hernandez AF AF Butler Butler J J Metra Metra M M et al et al Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy Eur J Heart Fail Eur J Heart Fail 2016 2016 18 18 3 3 290 290 297 297 10.1002/ejhf.456 10.1002/ejhf.456 26663359 26663359. This evidence concerns the gene EDN1 and hydrops fetalis.