EIF5A and acute respiratory distress syndrome: In short, the paper confirmed the upregulation of circPTK2 and eIF5A and downregulation of miR-766 in septic ALI models and innovatively proposed and demonstrated that circPTK2 knockdown reduces the release of inflammatory cytokines and inhibits pyroptosis through the miR-766/eIF5A axis, thereby inhibiting the progression of septic ALI.