Furthermore, mutations in Kv1.1 channels have been associated with epilepsy, and Kcna1-deficient mice are considered to be a model of sudden unexpected death in epilepsy (SUDEP), while also showing progressive respiratory dysfunction (Simeone et al., 2018; D’Adamo et al., 2020; Paulhus et al., 2020). The gene discussed is KCNA1; the disease is epilepsy.