NEFL and photosensitive epilepsy: A comparative analysis of several neuronal and glial proteins in adults with new-onset self-limiting seizures, chronic epilepsy, and PSE showed significant differences in NF-L between these conditions, with at least 2 years of follow-up demonstrating higher NF-L in PSE vs. self-limiting single seizure cases, and with overall levels of NF-L in patients with chronic epilepsy and PSE exceeding those in patients with single seizure episodes [74].