CD274 and breast carcinoma: Furthermore, there was a reduction of PD-L1 expression on CD45+ cells in MT-Kin-1fl/fl tumors (Figure 3—figure supplement 3B), as well as reduced PD-L1 on several myeloid subsets, demonstrating modulation of the PD-L1 pathway in Kindlin-1-deficient tumors also in this spontaneous breast cancer model.