For instance, tyrosine kinase FES and stabilin‐1 (STAB1) that activate phagocytosis (Park et al., 2009; van der Wel et al., 2020), ADP‐ribosylarginine hydrolase ADPRH that inhibits interferon‐gamma signaling (Menzel et al., 2021) for activating phagocytosis, and the less functionally characterized extracellular glycoprotein elastin microfibril interfacer 2 (EMILIN2) were significantly upregulated during the progression of cognitive decline (Figure 3j). Here, EMILIN2 is linked to Mental deterioration.