PBRM1, another component of the SWI/SNF complex, is found mutated in 41% of renal clear cell carcinomas, and sunitinib, a common clinical kidney cancer treatment, has no significant effect on PBRM1‐mutated renal clear cell carcinomas, but it is sensitive to anti‐VEGF drugs.71, 72. This evidence concerns the gene SMARCA1 and clear cell renal carcinoma.