BRD7, SMARCC2, ARID2, ACTL6A/B, SMARCC1, SMARCD1/2/3 are other key subunits of SWI/SNF, and recent studies have reported that mutations in these subunits cause gastric cancer (GC), colon cancer (CRC), hepatocellular carcinoma (HCC), head and neck squamous carcinoma (HSNC), breast cancer (BRCA) and other tumours.20, 21, 22, 23, 24, 25, 26, 27, 28, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53. The gene discussed is ACTL6A; the disease is hepatocellular carcinoma.