The COVID-19 mortality rate was associated with IL10 rs1800872 TT genotype in the Alpha (OR 2.06, 95% CI 1.42–2.98) and Omicron BA.4 (OR 10.81, 95% CI 6.73–17.36) variants and GT in the Alpha (OR 1.44, 95% CI 1.10–1.89) and Delta (OR 2.97, 95% CI 2.19–4.02) variants (Table 3). The gene discussed is IL10; the disease is COVID-19.