We then screened 10 PRGs with prognostic value, namely, AIM2, CASP3, CASP4, CASP5, CASP6, CASP8, GSDMC, IL18, NLRP2, and PYCARD, which were negatively associated with prognosis in patients with PAAD. This evidence concerns the gene PYCARD and pancreatic adenocarcinoma.