Moreover, Kaplan–Meier curves suggested a longer survival time in PAAD patients with low expression of AIM2 (Fig. 2A, P = 0.012), CASP3 (Fig. 2B, P = 0.009), CASP4 (Fig. 2C, P = 0.021), CASP5 (Fig. 2D, P = 0.035), CASP6 (Fig. 2E, P = 0.032), CASP8 (Fig. 2F, P = 0.034), GSDMC (Fig. 2G, P = 0.024), IL18 (Fig. 2H, P = 0.032), NLRP2 (Fig. 2I, P = 0.002), and PYCARD (Fig. 2J, P = 0.028). This evidence concerns the gene CASP8 and pancreatic adenocarcinoma.