We then screened 10 PRGs with prognostic value, namely, AIM2, CASP3, CASP4, CASP5, CASP6, CASP8, GSDMC, IL18, NLRP2, and PYCARD, which were negatively associated with prognosis in patients with PAAD. Here, CASP3 is linked to pancreatic adenocarcinoma.