On the other hand, since the Draxin mutation has been verified as the genetic cause for AgCC in BTBR/J and Draxin knockout mice show abnormalities in anxiety, spatial learning, and socio-emotional behaviors [66] (personal communication), we wondered whether BTBR/R is a better autism model, as it lacks the side effects of Draxin mutation. This evidence concerns the gene DRAXIN and Anxiety.