SOX11 and neuroblastoma: In keeping with the presumed gene regulatory activity of this super-enhancer region, the super-enhancer signal is correlated with SOX11 expression both in NB cell lines (r = 0.774, p = 8.39e-5, Fig. 2d) and tumors (r = 0.778, p = 1.25e-10, Fig. 2d), supporting a functional interaction between this enhancer region and SOX11 transcriptional regulation.