According to the publicly available CRISPR screen data in 1086 cell lines (CRISPR 22Q2 Chronos, available via the DepMap Portal)16, SOX11 is identified as a strongly selective gene with dependency in 25 NB cell lines and significantly selective for NB (p = 2.5e-40) and more specifically in 11 MYCN amplified NB cell lines (p = 7.4e29, Supplementary Fig. 3a). The gene discussed is MYCN; the disease is neuroblastoma.