SNAI1 and adenoma: In the BrafV637E-driven model of serrated intestinal cancer, we observed more invasive carcinomas in animals with aberrant SNAIL expression (Villin-Cre;LSL-BrafV637E/+;SnailKI/+; termed VBrafV637E/+;SnailKI/+) than in VBrafV637E/+ animals, and also more adenomas per animal (Supplementary Fig. S2a–f).