CircularRNA circ_0071269 knockdown is found to protect against from DCM by the microRNA-145/gasdermin A axis.18 In addition, the increased expression of circRNA_000203 in mouse diabetic hearts could enhance the expression of fibrosis-associated genes by sponging miR-26b-5p.19 A circRNA cerebellar degeneration-related protein 1 antisense (CDR1as) is found to be upregulated in DCM. The gene discussed is GSDMA; the disease is familial dilated cardiomyopathy.