CD24 and neoplasm: The CD24-sialic acid-binding immunoglobulin-like lectin-10 (Siglec-10) axis is known to protect the body from a lethal response involving pathological cell death.87 Recent studies indicated that blocking the binding of CD24 and Siglec-10 with a CD24 antibody significantly enhances the recognition of CD24-expressing tumor cells by macrophages, and after CD24 antibody treatment, the growth of murine orthotopic tumors was inhibited strikingly.