STC-1 is expressed highly in a variety of cancers, such as colon cancer,299 gastric cancer (GC),206 ovarian cancer,299 breast cancer,114 bladder cancer,300 glioblastoma,301 acute leukemia,302 and hepatocellular carcinoma, and higher expression of STC-1 relates to metastasis, lower survival rate and faster progression. This evidence concerns the gene STC1 and colonic neoplasm.