SLAMF7, also known as CD319, CS1 or CRACC, is a member of the SLAM family of receptors that are present on both tumor cells173–175 and immune cells, including NK cells, B cells, DCs, and activated CD4 and CD8 T cells.162 SLAMF7 on macrophages recognizes homotypic SLAMF7 on hematopoietic cells to mediate phagocytosis. The gene discussed is CD4; the disease is neoplasm.