Inflammation is involved in many diseases, such as infection, sepsis, liver injury, and chronic graft-versus-host disease; it is the innate immune response to pathogen infection and tissue damage, and CD24 is able to differentiate between DAMPs and pathogen-associated molecular patterns during inflammation.87 It selectively inhibits the host response to tissue injury via interaction with Siglec G (mouse) or Siglec10 (human). This evidence concerns the gene CD24 and infection.