CD47 and neoplasm: Chen et al. showed that during the CD47-SIRPα axis blockade, the phagocytosis of hematopoietic tumor cells was rigidly dependent on SLAMF7,175 but He et al. reported that SLAMF7 is not required for CD47-mediated phagocytosis.177 Given these controversial research results, the role of SLAMF7 in macrophage phagocytosis requires further investigation.