INS and type 2 diabetes mellitus: Regular physical activity helps not only prevent the onset of T2DM, but can also improve T2DM-related variables such as body mass index, glycemic control and variability, insulin sensitivity, lipid profile, oxidative stress/antioxidative capacity, and/or chronic inflammation (Bennetsen et al., 2020; Esefeld et al., 2021; Meuffels et al., 2022).