NLRP3 and COVID-19: In addition, activation of NLRP3 inflammasome by SARS-CoV-2 (P = 0.003) and host–pathogen interaction of human coronavirus interferon induction (P < 0.0001) canonical pathways was upregulated in T cells of COVID-19 subjects vs. healthy controls (SI Appendix, Fig. S1 B–D and Dataset S2).