Among patients with liver involvement, in multivariate logistic regression analysis with fetuin-A and the parameters used in the Nazer score (bilirubin, aspartate aminotransferase and prothrombin time) only fetuin-A was a significant determinant of having cirrhosis (Exp(B) = 0.973, CI = 0.948–0.999, p = 0.040). Here, F2 is linked to Cirrhosis.