Also, we conducted gene set enrichment analysis (GSEA) of HCC patients in different risk groups, and the result showed that high-risk group was enriched in Fc gamma R mediated phagocytosis, T cell receptor signaling pathway, Nod-like receptor signaling pathway, Fc epsilon Ri signaling pathway, while low risk group was enriched in PPAR signaling pathway and drug metabolism pathway (Figure 7C). This evidence concerns the gene PPARA and hepatocellular carcinoma.