CYB5D2 and neoplasm: K-M curves showed that upregulated TRNP1, CCDC112, CFL1 were associated with poor OS) and CYB5D2, SLC22A1 were protective genes (expression of CYB5D2, SLC22A1 were decreased in tumor tissues, and higher expression of CYB5D2, SLC22A1 was associated with good OS).