Due to highly expressed levels of LRRK2 protein in peripheral immune cells, in particular neutrophil and classical monocytes, and its recognized central role in several immune and infection processes [60], the peripheral and central inflammatory profiles have been evaluated not only in LRRK2-NMC but also in GBA1-NMC, as potential factors modulating disease risk. Here, LRRK2 is linked to nut midline carcinoma.