LRRK2 and Parkinson disease: In another 10-year longitudinal study conducted on Chinese communities composed by carriers of LRRK2-G2385R variant (329 subjects) or non-carriers (345 subjects), an increased PD risk for LRRK2-G2385R-NMC above 50 years of age (7.9%) compared with non-carriers (2.6%) was detected; however, no differences in motor or non-motor symptoms were observed between the two groups [39].