We further assessed whether YKL-40 would increase the predictive value of conventional risk factors including age, gender, history of hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, atrial fibrillation, smoking, drinking alcohol, baseline NIHSS, intravenous thrombolysis, SAP, and TOAST subtype (Table 3). This evidence concerns the gene CHI3L1 and coronary artery disorder.