IL2 and food allergy: Zhang et al. (2016) found that infants who went on to develop food allergy at 1 yr of life had hyper-inflammatory monocytes that could support Th2 skewing in the absence of IL-2 (Zhang et al., 2016). An altered monocyte phenotype in the context of established food allergy has also been described by Neeland et al. (2018, 2020).