In addition, A-FABP expression in CD11b+F4/80+MHCII-Ly6C- phenotype TAMs facilitates protumor IL-6/STAT3 signaling by regulating the NFkB/miR-29b pathway, and A-FABP deficiency significantly decreases the growth and spread of breast tumors in transgenic and syngeneic tumor models119. This evidence concerns the gene STAT3 and neoplasm.