Again, while tumor RANK expression was not associated with any of the clinicopathologic factors analyzed (Fig EV3B; Dataset EV1), in the ER‐NEGATIVE ONLY collection, patients with RANK+ tumors showed a significant poorer 10‐year survival compared with patients with RANK− tumors (Fig 2C), confirming the results of the NPS ER− subset (Fig EV3A). The gene discussed is ESR1; the disease is neoplasm.