A total of 1401 patients with minor stroke (NIHSS ≤5) and LVO within 4.5‐h time window were included for subsequent analysis and in Figure 1 the flowchart depicts the reasons for patient exclusion, including no LVO on baseline vessel imaging (n = 8348), NHISS ≥6 (n = 2135), TIA (n = 446), endovascular therapy including arterial thrombolysis and mechanical thrombectomy (n = 8), no intravenous t‐PA, DAPT or aspirin within 24 h (n = 473), and onset to door time >4.5 h (n = 2355). The gene discussed is PLAT; the disease is Stroke.