However, the tumor stromaltissue of area 1 contained particularly high concentrations of CD20+B-lymphocytes (500–1000 cells/mm2) and CD68+ macrophages(250–500 cells/mm2), followed by lower concentrations ofCD8+ cytotoxic T-cells (50–100 cells/mm2),FOXP3+ Tregs (30–80 cells/mm2), and T-bet+Th1-cells (10–50 cells/mm2) (Figures 2 and 3). The gene discussed is FOXP3; the disease is neoplasm.