The markers in the above case were only weakly positive and included RNP antibodies, antiscleroderma-70, and anti-centromere B antibodies, which are consistent with mixed connective tissue disease, scleroderma diffuse type, and scleroderma calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia (CREST) type. Here, RNPC3 is linked to connective tissue disorder.