While Csf1r was upregulated in non-AD littermates after Cre-mediated induced knock-out of miR-155 relative to vehicle controls (p = 0.0052), Csf1r expression remained unchanged in APP/PS1 microglia with miR-155 loss (p = 0.9755) and expression of Csf1r was significantly different from non-AD littermates (p = 0.0004). The gene discussed is PSEN1; the disease is Alzheimer disease.