Clusters 0, 3, 12 and 13 were related to transcriptional misregulation in cancer, acute myeloid leukemia, hematopoietic cell lineage, microRNAs in cancer and pathways in cancer (including the MAPK/PI3K-Akt/Rap1/p53/Ras/Phospholipase D signaling pathway). The gene discussed is TP53; the disease is acute myeloid leukemia.