To test our conjectures put forward above, we further screened potential targets of PABPN1 by the following criteria: (1) with at least 2 PASs in 3’UTR; (2) upregulated in BC; (3) undergoing significant lengthening in 3’UTRs upon PABPN1 overexpression (P < 0.001) (Fig. 3F, left panel). The gene discussed is PABPN1; the disease is breast cancer.