The results revealed a strong correlation between CD64+ Mφ (CD64+CD68+) density and immune-activated pathways (e.g., IFNγ response, cytotoxic cells, antigen presentation signals) and a negative association with pro-tumor signals (e.g., TGFβ, Wnt, tumor proliferation signals) (Fig. 4A, B). This evidence concerns the gene CD68 and neoplasm.