ELOVL6 and obesity due to melanocortin 4 receptor deficiency: Moreover, induction of obesity by high-fat diet feeding markedly altered the expression of each examined isoform of ELOVL, namely ELOVL1, ELOVL3, and ELOVL6 (+ 65.04%, + 36.19%, − 37.34% and + 65.81%, vs. the control group, respectively, p < 0.05; Fig. 7) in the white skeletal tissue.