To illustrate the correlation among DUSP14, ACOX1, and β-catenin in CRC, we used IHC of matched patient samples from the HPA dataset (Supplementary Fig. S9a) and validated the negative correlation between ACOX1 and DUSP14 and the negative correlation between ACOX1 and β-catenin (Supplementary Fig. S9b, c). Here, DUSP14 is linked to colorectal carcinoma.