In addition, we stained our three NSG-BL tumors, as well as NSG-Daudi tumors for cleaved caspase-3 by IHC, and observed increased caspase-3 cleavage in rituximab-treated NSG-BL740 tumors, as well as NSG-BL720 tumors but not BL717 (Fig 7C). The gene discussed is CASP3; the disease is Burkitt lymphoma.