In particular, PTEN‐induced putative kinase 1 (PINK1), which is linked to Parkinson's disease, mitochondrial homeostasis, the Warburg effect in cancer, the cell cycle, autophagy, and inflammatory responses [36], was identified as a key node connecting MFN2/UCP4 and other nodes in the regulation of calcium homeostasis. The gene discussed is PINK1; the disease is cancer.