CGAS and cervical squamous intraepithelial neoplasia: As CIN induction was shown to trigger IL-6 expression and the engagement of the pro-survival IL-6/JAK/STAT3 signalling axis [120, 121] in a cGAS–STING-dependent manner, it was posited that its activation may constitute a requirement to overcome the deleterious effects of CIN-induced STAT1.