Although it is unclear how universal a metastatic escape route this represents across different tumour types, CIN has also recently been reported to fuel cGAS–STING-dependent pro-metastatic inflammation in subsets of uveal melanoma (UM) [117] and pancreatic ductal adenocarcinoma (PDAC) [118], besides aggressive breast cancer [13]. The gene discussed is STING1; the disease is breast cancer.