PPT1 and atrial fibrillation: In line with these observations, gene therapy‐treated animals displayed a prominent reduction of AF storage in the brain as compared to Ppt1−/− untreated mice (Fig 5E and top graph in Fig 5F) and rescue of cortical thickness, with ICV+IV‐transplanted mice showing a slightly better improvement in all the three areas analyzed (namely somatomotor, somatosensory, and visual cortex), as compared to the IV‐transplanted mice (bottom graph in Fig 5F).