NFE2L2 and cancer: Cell experiments have showed that NPs from fungi could regulate Nrf2 antioxidant pathway for liver protection (192), lung protection (33, 105), cardioprotection (193), gastrointestinal protection (113), anti-oxidation (194, 195), anti-aging (108, 196, 197), anti-diabetic (102, 198), anti-cancer (199), and anti-atherosclerosis (29).