For the context-depend on partners of p-TEFb including NF-kB in many types of cancer cells (Barboric et al., 2001), SOX2 and SOX10 in Schwann cells (Arter and Wegner, 2015), Mediator both in serval cancer cells and pluripotent stem cells (Donner et al., 2010; Li et al., 2019), and c-MYC in pluripotent stem cells (Rahl et al., 2010). This evidence concerns the gene SOX2 and cancer.