At 8 weeks post-immunization (7 weeks post-transplantation), IMM-RIP-B7.1 mice which already had developed severe insulitis and hyperglycemia (Figure 1) displayed the highest increase of CD11b+ myeloid cells, CD4+ and CD8+ T Cells and CD19+ B Cells (Supplementary Figure S5). The gene discussed is CD4; the disease is Hyperglycemia.