CD80 and Hyperglycemia: In contrast, UC-MSC-transplanted IMM-RIP-B7.1 mice displayed a significantly reduced percentages of both [CD11b+/F4/80+/CD206-] and [CD11b+/Ly6C−/MHC-II+] inflammatory macrophages, which is in agreement with their reduced hyperglycemia as compared to non-transplanted IMM mice (Figures 7B, D).