MTOR and shigellosis: The pathways with top richness metabolites in the GC–MS platform were: Protein digestion and absorption, Glyoxylate and dicarboxylate metabolism, mTOR signaling pathway, Glycosaminoglycan biosynthesis-heparan sulfate/heparin, Alcoholic liver disease, Cholinergic synapse, Shigellosis, Oxidative phosphorylation, Valine, leucine and isoleucine biosynthesis, Taurine and hypotaurine metabolism (p < 0.05; Figure 6A).