PRKN and Parkinson disease: Genes involved with PD are parkin 2 (PARK2 or PRKN), gene encoding α-syn (SNCA or PARK1), leucin-rich repeat kinase 2 (LRRK2 or PARK8), glucocerebrosidase (GBA or PARK18), PTEN induced putative kinase 1 (PINK1 or PARK6), protein deglycase DJ-1 (or PARK7), and PARK-vacuolar protein sorting ortholog 35 (VSP35 or PARK17) (Klein and Westenberger, 2012).