Elucidation of the Wnt/mTOR signaling dysfunction underlying ADHD-AD overlapping pathophysiology is very important also as a contribution to understanding its role in the pathophysiology of other neurodegenerative disorders like Parkinson’s disease (Huang et al., 2022; Serafino and Cozzolino, 2023). This evidence concerns the gene MTOR and attention deficit-hyperactivity disorder.